Nitric oxide (NO) is a powerful signaling molecule with far reaching effects. Inspired by Cu and Zn environments in biology, we employ synthetic models that outline pathways to interconvert molecules in NO signaling such as nitrate, nitrite, and S-nitrosothiols (RSNO).
Current Team Members
Pokhraj Ghosh, PhD
examining nitrite and NO reduction at copper
Lewis acid facilitated reduction of NOx and species in H2S/NO crosstalk
modeling reduction of nitrite at copper
DFT modeling of heme-copper-NO systems