Team C-H

Through mechanistic understanding of reactive copper intermediates, we develop new reactions to directly convert sp3 C-H to C-C, C-N, C-O, and C-S bonds.  These methods offer unique synthetic opportunities for the late stage functionalization of organic molecules.

C-H.png
Cu-alkynyl.jpg
C-N formation.png
Bulky catalyst.png
alkynylation.png
C-N Method.png

Current Team Members

Isuri Jayasooriya 

iuj2@georgetown.edu

copper-catalyzed C-N and C-S bond formation

Bryan Figula

bcf37@georgetown.edu

copper-catalyzed C-C bond formation

Ting-An Chen 

tc850@georgetown.edu

copper-catalyzed C-C bond formation

YuJai Lin

yl1241@georgetown.edu

DFT studies of C-C bond formation at copper